Triplet-triplet annihilation upconversion followed by FRET for the red light activation of a photodissociative ruthenium complex in liposomes.

Triplet–triplet annihilation upconversion followed by FRET for the red light activation of a photodissociative ruthenium complex in liposomes† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5cp04352b

Red Light Activation of Ru(II) Polypyridyl Prodrugs via Triplet-Triplet Annihilation Upconversion: Feasibility in Air and through Meat.

Triplet-triplet annihilation upconversion (TTA-UC) is a promising photophysical tool to shift the activation wavelength of photopharmacological compounds to the red or near-infrared wavelength domain, in which light penetrates human tissue optimally. However, TTA-UC is sensitive to dioxygen, which quenches the triplet states needed for upconversion. Here, we demonstrate not only that the sensit...

Temperature Dependence of Triplet–Triplet Annihilation Upconversion in Phospholipid Membranes

Understanding the temperature dependency of triplet-triplet annihilation upconversion (TTA-UC) is important for optimizing biological applications of upconversion. Here the temperature dependency of red-to-blue TTA-UC is reported in a variety of neutral PEGylated phospholipid liposomes. In these systems a delicate balance between lateral diffusion rate of the dyes, annihilator aggregation, and ...

Photochemical Upconversion: A Physical or Inorganic Chemistry Experiment for Undergraduates Using a Conventional Fluorimeter

Photochemical upconversion is a regenerative process that transforms lower-energy photons into higher-energy light through two sequential bimolecular reactions, triplet sensitization of an appropriate acceptor followed by singlet fluorescence producing triplet−triplet annihilation derived from two energized acceptors. This laboratory directly investigates this phenomenon using the facile photo-...

Red-light-absorbing diimine Pt(II) bisacetylide complexes showing near-IR phosphorescence and long-lived 3IL excited state of Bodipy for application in triplet-triplet annihilation upconversion.

Bodipy is used for the preparation of Pt(II) bisacetylide complexes which show strong absorption of visible light and long-lived triplet state. Room temperature (RT) near-IR phosphorescence of Bodipy was observed. The π-conjugation framework of visible light-harvesting Bodipy ligand was connected to the Pt(II) center by the C≡C bond. The complexes were used as triplet photosensitizers for tripl...